|
|
leukotriene_A4 + H2O <=> leukotriene_B4
|
3.3.2.6
leukotriene-A4 hydrolase
|
–
|
MK
|
|
BRENDA:
BR48209
KEGG:
R03057
MetaCyc:
LEUKOTRIENE-A4-HYDROLASE-RXN
SABIO-RK:
2902
|
|
|
|
leukotriene_B4 + reduced_flavodoxin + O2 <=> 20-hydroxy-leukotriene_B4 + flavin + H2O
|
1.14.14.78
phylloquinone omega-hydroxylase
1.14.14.94
leukotriene-B4 20-monooxygenase
|
–
–
|
K
|
|
BRENDA:
BR36761
KEGG:
R03866
|
|
|
|
leukotriene_B4 + NAD+ <=> 12-Keto-leukotriene_B4 + H+ + NADH
|
not assigned
|
–
|
|
|
KEGG:
R03863
|
|
|
|
leukotriene_B4 + NADP+ <=> 12-Keto-leukotriene_B4 + H+ + NADPH
|
not assigned
|
–
|
|
|
KEGG:
R03864
|
|
|
|
leukotriene_B4 + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 20-hydroxy-leukotriene_B4 + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.94
leukotriene-B4 20-monooxygenase
|
–
|
|
|
MetaCyc:
LEUKOTRIENE-B4-20-MONOOXYGENASE-RXN
|
|
|
|
UDP-glucuronate + leukotriene_B4 <=> UDP + leukotriene_B4_beta-D-glucuronoside
|
2.4.1.17
glucuronosyltransferase
|
–
|
|
|
BRENDA:
BS436044
|
|
|
|
leukotriene_A4 + H2O <=> L-arginine + leukotriene_B4
|
3.4.11.6
aminopeptidase B
|
–
|
|
|
BRENDA:
BS382210
|
|
|
|
leukotriene_A4 + H2O <=> leukotriene_B4 + (5S,12R)-dihydroxy-6,10-trans-8,14,cis-eicosatetraenoic_acid
|
3.3.2.6
leukotriene-A4 hydrolase
|
–
|
|
|
BRENDA:
BS361335
|
|
|
|
leukotriene_A4 + H2O <=> (5S,6S)-dihydroxy-7,9-trans-11,14-cis-eicosatetraenoic_acid + leukotriene_B4 + (5S,12R)-dihydroxy-6,10-trans-8,14,cis-eicosatetraenoic_acid
|
3.3.2.6
leukotriene-A4 hydrolase
|
–
|
|
|
BRENDA:
BS361336
|
|
|
|
O2 + NADPH + leukotriene_B4 + H+ <=> H2O + NADP+ + 20-hydroxy-leukotriene_B4
|
1.14.14.94
leukotriene-B4 20-monooxygenase
|
–
|
|
|
SABIO-RK:
3615
|
|
|
|
H+ + NADH + leukotriene_B4 + O2 <=> 19-OH-Leukotriene_B4 + H2O + NAD+
|
1.14.14.94
leukotriene-B4 20-monooxygenase
|
–
|
|
|
SABIO-RK:
6519
|
|
|
|
H+ + NADH + leukotriene_B4 + O2 <=> NAD+ + H2O + 20-hydroxy-leukotriene_B4
|
1.14.14.94
leukotriene-B4 20-monooxygenase
|
–
|
|
|
SABIO-RK:
6521
|
|
|
|
H+ + O2 + leukotriene_B4 + NADPH <=> 19-OH-Leukotriene_B4 + H2O + NADP+
|
1.14.14.94
leukotriene-B4 20-monooxygenase
|
–
|
|
|
SABIO-RK:
8182
|
|